Abstract. Although the possible link between panic disorder and mitral valve prolapse has attracted considerable research interest, the reported prevalence of mitral valve prolapse among patients with panic disorder is wide-ranging and is not fully understood. Clinical and epidemiological studies provide conflicting evidence of a possible association or definite cause and effect relationship between these two diseases. The large variability in the results can be explained by various factors. Although there is no convincingly supported cause and effect hypothesis so far, there are several possible reasons for the hypothetical relationship between the two conditions. The data obtained so far is not sufficient to establish or disconnect the two states.

Key words: panic disorder, mitral valve prolapse

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