Abstract. Optical coherence tomography (OCT) is an indispensable diagnostic method in the ophthalmic practice, which is based on low-coherence interferometry, providing a layered image of eye tissues on a micron scale, comparable to a histological sec on. Over the past decade OCT has been widely used in the diagnosis and follow-up of patients with multiple sclerosis and op c neuritis. The topic of progression of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease and schizophrenia is becoming more and more relevant. The objective, easily reproducible assessment, which does not pose additional risks, is progressively demonstrating its potential in retinal research as a possible biomarker for early diagnosis and for tracking the degenerative process, and is likely to reveal future horizons in relation to therapy and better prognosis for these patients.

Кey words: OCT, Alzheimer’s, Parkinson’s, schizophrenia, neurodegeneration

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